Designing clinical-grade integrated strategies for the downstream processing of human mesenchymal stem cells
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چکیده
منابع مشابه
Designing clinical-grade integrated strategies for the downstream processing of human mesenchymal stem cells
Background During the past decade, human stem cells have been the focus of an increased interest due to their potential in clinical applications, as a therapeutic alternative for several diseases. Within this context, human mesenchymal stem cells (hMSCs) have gained special attention due to their immune-modulatory characteristics, as well as in secreting bioactive molecules with anti-inflammato...
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There are two main categories for stem cells a cording to their origin: Embryonic Stem Cells and Adult Stem Cell. Mesenchymal stem cell, supporting hematopoetic stem cells in bone marrow, can regenerate tissues such as bone, cartilage, muscle, tendon and fatty tissue. These cells were recognized for the first time by Friedenstein and Petrokova who could isolate theme from rat bone marrow.Mesenc...
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in this study, our aim was to produce a generation of gmp-grade adipose tissue-derived mesenchymal stem cells for clinical applications. according to our results, we fulfill to establish consistent and also reproducible current good manufacturing practice (cgmp) compliant adipose tissue-derived mesenchymal stem cells from five female donors. the isolated cells were cultured in dmem supplemented...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2013
ISSN: 1753-6561
DOI: 10.1186/1753-6561-7-s6-p103